Active Ingredient	Aglepristone
Manufacturer	Virbac
Origin	Australia
Reference	N/A

What is Alizin (Aglepristone) used for?

Alizin (Aglepristone) is used in female dogs as an emergency contraceptive. When used within the first 45 days after mating, it can terminate a unwanted pregnancy. Alizin blocks the female sex hormone progesterone, which results in the loss of pregnancy.

How should I use Alizin (Aglepristone)?

Alizin comes in a 10mL vial. Each mL contains 30mg of the active ingredient Aglepristone.

Alizin should be injected subcutaneously (under the skin) at a dosage of 10mg (0.33mL of solution) per kg of bodyweight (to a maximum of 5mL of solution). The same dosage should then be repeated 24 hours later.

Abortion or resorption occurs within 7 days after the injection. Have your vet check that this has occured.

What are the side effects of Alizin (Aglepristone)?

Some side effects that may result from the use of Alizin in dogs include:

• anorexia
• excitations
• depression
• diarrhea
• vomitting
• pain and/or inflammation at the injection site
• haematological changes including neutrophilia, neutropaenia, thrombocytosis, haematocrit variation, lymphocytosis, lymphopaenia
• biochemical changes such as changes in urea, creatinine, chloride, potassium, sodium, ALT, ALP, AST

Please Note

Alizin should not be used until after the end of oestrus. Avoid any new mating before the end of oestrus. This is to minimize the possibility of lack of expected efficacy.

In some cases, partial abortions can happen. Have your vet check that a full abortion has occured. If it hasn't subsequent treatments might be needed.

Alizin is for treatment of dogs only. It must not be taken by humans. Pregnant women must be very careful not to contact the solution when administering Alizin.

Dogs with impaired hepatic function or impaired renal function should not take Alizin.

Alizin should not be given to dogs with manifest or latent hypoadrenocorticism (Addison's disease) or in dogs with a genetic predisposition to hypoadrenocorticism.