What is Votrient (Pazopanib) used for?
Votrient is a cancer medicine used to treat certain types of cancer. It can be used to treat patients who have advanced renal cell carcinoma. It can also be used to treat patients who have advanced soft tissue sarcoma who have already received prior chemotherapy. The active ingredient in Votrient is Pazopanib.
How should I use Votrient (Pazopanib)?
When treating patients with renal cell carcinoma, the starting dosage of Votrient is usually 800mg daily. After the loading dose has been reached, the dosage can be reduced by 400mg, and then further decreased or increased in 200mg increments until a desirable level is reached.
When treating patients with soft tissue sarcoma, the starting dosage of Votrient is usually 800mg daily. After the loading dose has been reached, the dosage can be reduced or increased in 200mg increments until a desired level is reached.
Votrient are oral tablets and should be taken on an empty stomach (one hour before or two hours after a meal).
Patients with hepatic impairment may require different dosages from patients with healthy hepatic function.
What are the side effects of Votrient (Pazopanib)?
Signs of an allergic reaction including hives, difficult breathing, or swelling of the face, lips, tongue, or throat will require urgent medical attention.
More serious side effects of Votrient include:
If you notice any of the above side effects, contact your doctor as soon as possible.
Less severe side effects you may notice can include:
Fatal hepatotoxicity has been observed in clinical trials. Blood tests to monitor hepatic function should be scheduled regularly.
Pazopanib is not recommended during pregnancy as there is a chance of it harming the unborn baby. It is uncertain if Pazopanib is passed through breastmilk.
Tell your doctor is of all medicines you are currently taking, especially any blood thinners as Votrient can interfere with wound healing.