Active Ingredient	Vinblastine Sulphate
Manufacturer	Cipla
Origin	India
Reference	N/A

What is Cytoblastin Injection (Vinblastine Sulphate) used for?

Cytoblastin is a cancer drug used to treat various forms of cancer including Hodgkin's disease, lymphocytic lymphoma, histiocytic lymphoma, mycosis fungoides, carcinoma of the testes, Kaposi's sarcoma and Letterer-Siwe disease (histiocytosis X). Vinblastine Sulphate (a vinca alkaloid) works by works by inhibiting microtubule formation in the mitotic spindle within cancer cells. This prevents their replication and slows the spreading of the disease.

How should I use Cytoblastin Injection (Vinblastine Sulphate)?

Cytoblastin can only be administered by intravenous injection. If Vinblastine is administered via any other route it can become fatal.

Your individualized dosage will be prescribed by your doctor and is dependant on the typ eof cancer being treated and a variety of personal factors. A starting dosage 3.7mg/m2 of body surface area is often prescribed for adults, but this is a guideline only. Follow the exact instuctions provided by your doctor. Do not exceed a maximum dose of 18.5 mg/m2 body surface area.

What are the side effects of Cytoblastin Injection (Vinblastine Sulphate)?

Side effects that have been reported with use of Cytoblastin (Vinblastine) include:

• leucopenia
• anaemia
• thrombocytopenia
• alopecia
• paresthesias
• constipation
• hypertension
• malaise
• bone pain
• weakness
• pain in tumor-containing tissue
• dizziness
• jaw pain

Please Note

Only ever give Cytoblastin via intravenous injection. Fatality can occur if Vinblastine is administered in any other way.

Cytoblastin is contraindicated in patients with significant granulocytopenia. The exception to this is if the granulocytopenia is present as a result of the underlying cancer.

If bacterial infection is present, this must be completely treated before administering vinblastine sulfate.